A World made penniless by that departure — Molecular Theory

A World made penniless by that departure 1
Of minor fabrics begs
But sustenance is of the spirit
The Gods but Dregs
(F.1642/J.1623)
[1] departure:: the starting on a course of action or thought (OED 1839).
[2] minor fabrics begs:: searches into the micro-structure of substance.
[3] spirit:: the essential part. sustenance:: solid material.
[4] Dregs:: refuse, residue, the most worthless part of anything. Gods but Dregs:: if material is made of atoms, as stated by the Molecular Theory (or Atomic Theory), then Gods, the spirit that cannot be seen, are dregs.

The Molecular Theory. The idea that matter is an aggregate of minute particles, each of which possesses all the essential properties of the mass, is as old as Democritus, but it was left for the present century to crystallize the conception of the atom in clear and accurate expression. ─ Popular Science (1879)